A large family from Texas reported of a severe hereditary bleeding disorder back in 2001 that made them suffer from nosebleeds, bruising and massive blood loss due to injury or surgery which required blood transfusions. Routine tests for functional components of the blood coagulation pathway did not reveal any obvious defects. Genomic sequencing revealed a mutation in the gene encoding coagulation factor 5 (FV), but it was not considered to contribute to disease, ...
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titled Swedish Researchers Track Down Origin of Hereditary Bleeding Disorder in a Texas Family.
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editor - Friday, August 30, 2013
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