Toxicity of DNA Drug on Liver can be Predicted Through a Novel Approach

A new study published in the journal Nucleic Acid Therapeutics reports on the development of a machine learning-based approach that can be used to predict the hepatotoxic potential antisense oligonucleotides drugs based on its chemical sequence. Peter Hagedorn and coauthors from Santaris Pharma, Hrsholm, Denmark, and University of Copenhagen, Denmark, describe the use of machine learning techniques to develop a method of classifying therapeutic oligonucleotides ...

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