Two biological mechanisms have been identified by researchers from Boston and at Johns Hopkins as the major cause of protein citrullination which triggers the immune system; driving the cascade of events leading to rheumatoid arthritis. In a report to be published online in the journal iScience Translational Medicine/i on Oct. 30, the research team describes how it found pore-forming pathways in cell membranes that are associated with the abnormal citrullination ...
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