Sunday, December 8, 2013

Cancerous Cells Use a Different Pathway for Genome Duplication

The process of genome replication occurs at structures called 'replication forks'. The latter are equipped with enzymes and move along the separated DNA strands. In tumour cells, the replication forks are frequently damaged, giving rise to breaks in the double-stranded DNA. An international study led by Thanos Halazonetis, Professor at the Faculty of Sciences at the University of Geneva (Switzerland), has revealed how cancer cells repair the damaged replication ...

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