Friday, December 6, 2013

In ALS Disease Silent RNAs Express Themselves When Stowed In Cytoplasmic Granules

RNA molecules are used by cells to make proteins. They are generally thought to be "silent" when stowed in cytoplasmic granules. But a protein mutated in some ALS patients forms granules that permit translation of stored RNAs, according to a study in emThe Journal of Cell Biology/em/a. The finding identifies a new mechanism that could contribute to the pathology of the disease. ALS, often referred to as "Lou Gehrig's Disease," is a progressive neurodegenerative ...

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