Sickle Cell Trait Could be Responsible for Higher Dosing of Anemia Drugs Among African-American Dialysis Patients

A new study published in the Journal of the American Society of Nephrology suggests that one of the major reasons why African Americans who are on dialysis require higher doses of an anemia medication could be due to the presence of sickle cell trait. Sickle cell trait represents the carrier state of sickle cell disease and is present in roughly 6% to 8% of African Americans. In sickle cell disease, individuals have two copies of a genetic mutation that produces ...

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