Wednesday, June 25, 2014

Mutated X-linked Mental Retardation Protein and How It Impairs Neuron Function

Malfunctions in brain cells that contribute to intellectual disability and other brain disorders have now been studied better. Professor Linda Van Aelst of Cold Spring Harbor Laboratory (CSHL) has been scrutinizing how the normal version of a protein called OPHN1 helps enable excitatory nerve transmission in the brain, particularly at nerve-cell docking ports containing AMPA receptors (AMPARs). Her team's new work, published June 24 in the emJournal of Neuroscience/em, ...

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