Pancreatic Cancer Resistance Mechanism Discovered

The University of Texas MD Anderson Cancer Center scientists have identified the pancreatic cancer resistance mechanism. Pancreatic cancer addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene. When researchers dialed up mutant Kras to spur pancreatic cancer growth in mice, and then shut it down, a group of recurrent tumors grew back independently ...