At Cold Spring Harbor Laboratory (CSHL), researchers have discovered a new function of the body's most important tumor-suppressing protein. Called p53, this protein has been called "the guardian of the genome." It normally comes to the fore when healthy cells sense damage to their DNA caused by stress, such as exposure to toxic chemicals or intense exposure to the sun's UV rays. If the damage is severe, p53 can cause a cell to commit preprogrammed cell-death, ...
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