Researchers have found that the activity of a protein called PPAR (and) #947; in pro-opiomelanocortin (POMC) neurons was crucial in regulating metabolic response to high fat diet, a new study published in the Journal of Clinical Investigation reveals. Sabrina Diano and colleagues at Yale University School of Medicine found that mice lacking PPAR (and) #947; specifically in POMC neurons gained less weight, were more active, and had improved glucose metabolism when fed a high-fat ...
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