Mutations in the isocitrate dehydrogenase (IDH) gene contribute to the formation of benign tumors in cartilage that can be a precursor to malignancies, reveal researchers. In a study published in the Feb. 16, 2015, issue of the iProceedings of the National Academy of Sciences/i, Duke researchers and their colleagues have shown how gene mutations may cause common forms of cartilage tumors. These benign tumors, known as enchondromas, are associated ...
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