B cell-mediated autoimmune diseases and lymphoma can now be treated using antibodies against B cell protein CD20. Antibody binding receptors, called Fc receptors, on other immune cells bind anti-CD20 on coated B cells, which induces B cell deletion through a mechanism that is not clearly understood. In this issue of the iJournal of Clinical Investigation/i, Philippe Bousse and colleagues at the Pasteur Institute in Paris described the fate of B cells in live ...
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titled Liver Tropism-The Key for B Cell Deletion Immunotherapy.
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editor - Saturday, November 2, 2013
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