Changes in the nervous system and age-related cognitive decline are closely linked, but up until recently, they were thought to result from the loss of neurons in areas such as the prefrontal cortex, the part of the brain important in working memory. A series of papers have shown that the "loss of neurons" concept is simply not true. Now, Mount Sinai scientists have begun to look elsewhere, focusing instead on synaptic health in the prefrontal cortex. Their work, ...
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titled Age-Related Cognitive Decline Linked to Energy in Synapses in Prefrontal Cortex.
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