
The existing mouse models of cancer have been compared to human cancer samples by researchers from the Fred Hutchinson Cancer Research Center in Seattle. These genetically engineered mouse models (which usually either overexpress a cancer-causing gene-or "oncogene"-or carry a deletion for a "tumor suppressor" gene) have been extensively used to understand human cancer biology in studies of drug resistance, early detection, metastasis, and cancer prevention, as well ...
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titled Basic Differences Between Human Cancers and Genetically Engineered Mouse Models Identified.
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Saturday, December 7, 2013
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