Valproic acid, used widely in treating epilepsy, has been found to reduce fat accumulation in the liver and lower blood sugar levels in the blood of obese mice, a new study reveals. Studying the ways in which the cytochrome P450 family of enzymes processes valproic acid, the Johns Hopkins biochemists found that it can activate the protein AMPK, which was already known to be a good drug target for treating metabolic disorders like type 2 diabetes and obesity. The ...
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editor - Friday, January 31, 2014
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