Sickle Cell Disease Can Be Precisely Targeted By Newly Discovered Gene Regulator

A new genetic target for potential therapy of sickle cell disease (SCD) was discovered by a research team from Dana-Farber/Boston Children's Cancer and Blood Disorders Center and other institutions. The target, called an enhancer, controls a molecular switch in red blood cells called BCL11A that, in turn, regulates hemoglobin production. The researchers-led by Daniel Bauer, MD, PhD, and Stuart Orkin, MD, of Dana-Farber/Boston Children's-reported their findings ...

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Written by: editor - Wednesday, October 16, 2013

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