Leukemia Cells Exploit 'Enhancer' DNA Elements to Cause Lethal Disease

At Cold Spring Harbor Laboratory (CSHL), a team of researchers has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML). AML is a devastating cancer that is incurable in 70% of patients. Just as important, the findings offer a mechanistic insight into how a new class of promising drugs - one version of which is already in human clinical trials - appears to halt ...

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Written by: editor - Thursday, November 28, 2013

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