A new study published in the journal Science Translational Medicine reports that the activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, leads to a lasting and harmful change in the immune system. An increase in beta-catenin in certain types of T cells-a class of white blood cells-causes chronic inflammation in the intestine and colon, eventually leading to cancer. The same mechanism is used by colon cancer to propagate itself. ...
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titled Activation of Beta-Catenin Leaves Lasting and Harmful Effect on Immune System.
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Thursday, February 27, 2014
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