Huntington Proteins and Their Nasty Interactions

Thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease (HD), have been identified and categorized by researchers at the Buck Institute. To use an analogy of a human social network, the identified proteins are like "friends" and "friends of friends" of the HD protein. The network provides an invaluable resource for identifying targets to treat the disease and has been used to implicate a particular signaling pathway involved ...