A new way of treating cancer has been identified by a team of researchers from five Swedish universities, led by Karolinska Institutet and the Science for Life Laboratory. The concept is presented in the journal iNature/i and is based on inhibiting a specific enzyme called MTH1, which cancer cells, unlike normal cells, require for survival. Without this enzyme, oxidized nucleotides are incorporated into DNA, resulting in lethal DNA double-strand breaks in cancer ...
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Thursday, April 3, 2014
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