Anti-CTLA-4 Cancer Immunotherapy Outcome Predicted With T Cell Repertoire Changes

Effects of anti-CTLA-4 antibody on the number and types of T cells present in patient's blood was investigated using LymphoSIGHT immune repertoire sequencing platform, from Sequenta, Inc., as the company announced publication of a study done in collaboration with researchers from UCSF and UCLA. The results, which appear in the May 28 issue of iScience Translational Medicine/i, shed light on the mechanism of action of this type of cancer immunotherapy and suggest that immune ...

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Written by: editor - Thursday, May 29, 2014

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