Excessive Activity of Repair Cells in Tissue Recovery Linked With Fibrosis

A new study published in The Journal of Cell Biology reveals that the activation of an important growth factor triggered by the excessive activity of repair cells in the early stages of tissue recovery leads to the onset of fibrosis. Myofibroblasts are highly contractile cells that repair damaged tissues by replacing and reorganizing the extracellular matrix (ECM), the meshwork that fills the space around cells, in order to draw a wound closed. When myofibroblasts ...

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Written by: editor - Friday, October 24, 2014

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