Research has shown that integrins, which are adhesion molecules expressed on the surface of cells, play a crucial role in "integrating" the cell exterior and the interior cytoskeleton in cells. The beta2-integrin family members are highly expressed in dendritic cells that are very important in immune responses. Dendritic cells pick up antigens in inflamed tissues and move to lymph nodes where they present the antigen to T cells and activate them to help fight infection. ...
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titled Research Reveals Integrins Losing Their Grip Leads to Activation of T Cell Immune Response.
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Thursday, October 30, 2014
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