» » Vincristine Induced Peripheral Neuropathy Linked With Gene Variant in Children With Acute Lymphoblastic Leukemia

Vincristine Induced Peripheral Neuropathy Linked With Gene Variant in Children With Acute Lymphoblastic Leukemia

A new study has revealed that children with acute lymphoblastic leukemia (ALL) who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug vincristine. Vincristine is widely used and an effective anticancer agent for treating leukemias in both adults and children. The dose-limiting toxic effect of the drug is peripheral neuropathy (damage to the nerves), characterized by neuropathic ...

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Written by: editor - Tuesday, February 24, 2015

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