In current medical practice, the standard treatment for chronic pain is a class of drugs called opioids. Patients on opioids for long periods of time become desensitized to these drugs or become paradoxically hypersensitive to pain (hyperalgesia); however, the adaptive mechanisms are not well understood. In this issue of the iJournal of Clinical Investigation/i, Yuan-Xiang Tao and colleagues from the New Jersey Medical School at Rutgers University ...
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titled Activation of MTOR Linked to Opioid Tolerance and Pain Hypersensitivity.
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editor - Friday, January 3, 2014
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