Tumors Suppressed By Mdm2 By Pulling The Plug On Glycolysis

Glycolysis, or the rates of energy-generating metabolic pathway, has been known to be higher in Cancer cells. This enhanced glycolysis, a phenomenon known as the Warburg effect, is thought to allow cancer cells to survive the oxygen-deficient conditions they experience in the center of solid tumors. A study in The Journal of Cell Biology reveals how damaged cells normally switch off glycolysis as they shut down and shows that defects in this process may contribute to the early ...

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Written by: editor - Wednesday, February 26, 2014

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